BIOGRAPHICAL SKETCH
Current Position:
Research Associate Professor, Department of Otolaryngology
Research Associate Professor (Joint), Program in Audiology and Communication Sciences
Education:
B.S., Physiology, Nanjing University, 1984
M.S., Physiology, Nanjing University, 1987
Ph.D., Neuroscience, University of Florida, 1992
Links:
http://otocore.wustl.edu/
RESEARCH INTERESTS
Aging and presbycusis (click for more information)
Click here for information on Dr. Bao's Lab.
PUBLICATIONS:
Jin, D., Lin, Z., Lei, D., and Bao, J. The role of glucocorticoids for spiral ganglion neuron survival. Brain Research, 2009, 3-11.
Xu, J., Chen, S., Chen, H., Xiao, Q., Hsu, C., Michael, D., and Bao, J. STAT5 mediates antipoptotic effects of methylprednisolone on oligodendrocytes. J. Neuroscience, 2009, 29(7), 2022-2026.
Bao, J. Signal transduction by the cytoplasmic domain of Neuregulin-1 and its roles during neuronal aging. Current Signal Transduction Therapy, 2007, 2.
Shen, H., Zhang, B., Shin, J., Lei, D., Du, Y., Gao, X., Dai, C., Ohlemiller, K., and Bao, J. Prophylactic and therapeutic functions of T-type calcium channel blockers on noise-induced hearing loss. Hearing Research, 2007, 226(1-2): 52-60.
Gagnon, P., Simmons, D., Bao, J., Lei, D., Ortmann, A., and Ohlemiller, K. Temporal and genetic influences on protection against noise-induced hearing loss by hypoxic preconditioning in mice. Hearing Research, 2007, 226 (1-2): 79-91.
Liu, J., Shin, J., Hyrc, K., Liu, S., Lei, D., Holley, M.C., and Bao, J. (2006) Stem cell therapy for hearing loss: Math1 over-expression in VOT/E36 cells. Otology and Neurotology, 2006, 27:416-423.
Han, M., Schottler, F., Lei, D., Dong, E., and Bao, J. Bcl-2 over-expression fails to prevent age-related loss of calretinin positive neurons in the dentate gyrus. Molecular Neurodegeneration, 2006, 1:1-9.
Bao, J., Lei, D., Du, Y., Ohlemiller, K., Beaudet, A., and Role, L. Requirement of nicotinic acetylcholine receptor subunit beta2 in the maintenance of spiral ganglion neurons during aging. J. Neuroscience, 2005, 25(12):3041-3045.
Bao, J., Lin, H., Quyang, Y., Lei, D., Osman, A., Kim, T., Mei, L., Dai, P., Ohlemiller, K.K., Ambron, R.T. Activity-dependent up-regulation of PSD-95 by
Neuregulin-1 and Eos. Nature Neuroscience, 2004, 7: 1250-1258.
Bao, J., Talmage, D.A., and Role, L.W. Nuclear signaling by the cytoplasmic domain of NRG-1. J. Cellular Biology, 2003, 161(6) 1133-1141.
Lin, H., Bao, J., Ju-Sung, Y., Walters, E., and Ambron, R.T. Rapid electrical and delayed molecular signals regulate the serum response element after nerve injury: convergence of injury and learning signals. J. Neurobiology, 2003, 57(2) 204-220.
Lee, Y.L., Shih, K., Bao, J., Ghirnikar, R.S., and Eng, L.F. Cytokine/chemokine expression in contused rat spinal cord. Neurochemistry International, 2000, 36(4-5), 417-425.
CONTACT INFORMATION
Jianxin Bao, Ph.D.
Washington University School of Medicine
Department of Otolaryngology
Center for Aging
Campus Box 8115, 660 S. Euclid Ave.
St. Louis, MO 63110
Phone: (314) 747-7199
Fax: (314) 747-7230
Email address: jbao@wustl.edu