BIOGRAPHICAL SKETCH

Current Position:
Research Associate Professor, Department of Otolaryngology
Research Associate Professor (Joint), Program in Audiology and Communication Sciences

Education:
B.S., Biology, Indiana University, 1983
Ph.D., Neuroscience, Northwestern University, 1990

Links:
http://otocore.wustl.edu/

RESEARCH INTERESTS

Environmental and genetic determinants of age-related and noise-induced hearing loss; mechanisms of cochlear injury; regulation of oxidative radicals in the mammalian cochlea



Click here for more information on Dr. Ohlemiller's Lab.

PUBLICATIONS:

Bao, J., D. Lei, Y. Du, Y., K.K. Ohlemiller, A.L. Beaudet, and L.W. Role (2005) Requirement of nichotinic acetylcholine receptor subunit 2 in the maintenance of spiral ganglion neurons during aging. Journal of Neuroscience 25: 3041-3045.

Zhu, Y., K.K. Ohlemiller, B.K. McMahan, T.S. Park, and J.M. Gidday (2006) Constitutive nitric oxide synthase activity is required to trigger ischemic tolerance in mouse retina. Experimental Eye Research 82: 153-163.

Grady, R.M., K.K. Ohlemiller, D.F. Wozniak, and J.R. Sanes (2006) Cerebellar synaptic defects and abnormal motor behavior in mice lacking - and -dystrobrevin. Journal of Neuroscience 26: 2841-2851.

Ohlemiller, K.K., J.M Lett and P.M. Gagnon (2006) Cellular Correlates of Age-Related Endocochlear Potential Reduction in a Mouse Model Hearing Research 220: 10-26.

Gagnon, P.M., D.D. Simmons, J. Bao, D. Lei, A.J. Ortmann and K.K. Ohlemiller (2007) Temporal and Genetic Influences on Protection against Noise-Induced Hearing Loss by Hypoxic Preconditioning in Mice. Hearing Research 226: 79-91.

Shen, H., B. Zhang, J.-H. Shin, D. Lei, Y. Du, X. Gao, Q.Wang, K.K. Ohlemiller, J. Piccirillo and J. Bao (2007) Prophylactic and therapeutic functions of T-type calcium blockers on noise-induced hearing loss. Hearing Research 226: 52-60.

Ohlemiller, K.K. and P.M. Gagnon (2007) Genetic dependence of cochlear cells and structures injured by noise. Hearing Research 224: 34-50.

Ogilvie, J.M., K.K Ohlemiller, G.N. Shah, B. Ulmasov, T.A. Becker, A. Waheed, A.K. Hennig, P.D. Lukasiewicz and W.S. Sly (2007) Carbonic anhydrase XIV deficiency produces a functional defect in the retinal light response. Proceedings of the National Academy of Sciences 104: 8514-8519.

Heldermon, C.D., A.K. Hennig, K.K. Ohlemiller, J.M. Ogilvie, E.D. Herzog, A. Breidenbach, C. Vogler and M.S. Sands (2007) Sensory, motor and behavioral deficits in the murine model of Sanfillipo syndrome Type B. PLoS ONE 2(8): e772. doi:10.1371/journal.pone.0000772.

Ohlemiller, K.K, M. E. Rybak Rice, and P. M. Gagnon (2008) Strial microvascular pathology and age-associated endocochlear potential decline in NOD congenic mice. Hearing Research 244: 85-97.

Herati, R.S, X. Ma, M. Tittiger, K.K Ohlemiller, A. Kovacs and K.P. Ponder (2008) Improved retroviral vector design reduces an immune response after adult gene therapy in Mucopolysaccharidosis I mice. Journal of Genetic Medicine 10: 972-982.

Meyerrose, T., M. Roberts, K.K. Ohlemiller, C. Vogler, Carole. J. Nolta and M.S. Sands (2008) Lentiviral-transduced human mesenchymal stem cells persistently express therapeutic levels of enzyme in a xenotransplantation model of human disease. Stem Cells 26: 1713–1722.

Ohlemiller, K.K., M.E. Rybak Rice, J.M Lett and P.M. Gagnon (2009) Absence of strial melanin coincides with age-associated marginal cell loss and endocochlear potential decline. Hearing Research 249:1-14.

CONTACT INFORMATION

Kevin K. Ohlemiller, Ph.D.
Fay and Carl Simons Center for the Biology of Hearing and Deafness/
Dept. of Otolaryngology
Washington University School of Medicine
Campus Box 8115, 660 S. Euclid Ave.
Saint Louis MO 63110

Phone: (314) 747-7179
Fax: (314) 747-7230
Email address: kohlemiller@wustl.edu