BIOGRAPHICAL SKETCH
Current Position:
Lindberg Professor and Head, Department of Otolaryngology
Professor (Joint), Program in Audiology and Communication Sciences
Education:
B.S., University of California at Berkely
M.D., University of Southern California, 1969
Ph.D., Medical Sciences, University of Minnesota, 1977
Links:
http://otocore.wustl.edu/
http://ent.wustl.edu/oto/otoweb.nsf/746682188a1bff2786256c5500627633/ae9cc1ddb8dba26d8625734c0068ae2b?OpenDocument
RESEARCH INTERESTS
Cellular and molecular biology of bone remodeling in cholesteatoma (click for more information)
Pseudomonas infections in the ear
Otology, Neurotology, reconstruction of the middle ear, petrous apicitis, otosclerosis, cholesteatoma, Meniere's disease, cochlear implants, bone anchored hearing aids
Cochlear implants – Improving surgical results
Click here for more information on Dr. Chole's Lab
PUBLICATIONS:
Nason R, Yung JY, Chole RA. Lipopolysaccharide-Induced Osteoclastogenesis from Mononuclear Precursors: A Mechanism for Osteolysis in Chronic Otitis. Journal of the Association of Research in Otolaryngology, January, 2009.
Chole RA, Nason R. Chronic Otitis Media and Cholesteatoma in Ballenger's Otorhinolaryngology-Head and Neck Surgery, 17th Edition – Centennial Edition (Chapter 17), 2009.
Finley CC, Holden TA, Holden LK, Whiting BR, Chole RA, Neely JG, Hullar TE, Skinner, MW. Role of electrode placement as a contributor to variability in cochlear implant outcomes. Otology & Neurotology, 29:7, 920-928, July, 2008.
Chole RA, Olomu O, Wang E. Bacterial biofilm infections in otology. Recent Advances in Otolaryngology, pgs 21-31, 2008.
Wang EW, Agostini G, Olomu O, Runco D, Jung JY, Chole RA. Gentian violet and Ferric ammonium citrate disrupt P. aeruginosa biofilms. Laryngoscope 118, 2008.
Nason R, Chole RA. Bacterial Biofilms May Explain Chronicity in Osteoradionecrosis of the Temporal Bone, Otol Neurotol, Sept 24, 2007.
Hartman JM, Yu, JW, Chole RA. Headache & Facial Pain in Ballenger's Otorhinolaryngology-Head and Neck Surgery, 17th Edition (Chapter 48), 2007.
Zhuang L, Jung JY, Wang EW, Houlihan P, Ramos L, Pashia M, Chole RA. Pseudomonas aeruginosa Lipopolysaccharide Induces Osteoclazstogenesis Through a Toll-Like Receptor 4 Mediated Pathway in Vitro and in Vivo, Laryngoscope, 117:841-847, May, 2007.
Tinling SP and Chole RA. Gerbilline Cholesteatoma Development III. Increased proliferation index of basal keratinocytes of the tympanic membrane and external ear canal, accepted Oto-Head & Neck Surg, February, 2006.
Tinling SP and Chole RA. Gerbilline Cholesteatoma Development II. Temporal histopathologic changes in the tympanic membrane and middle ear, Oto-Head & Neck Surg, February, 2006.
Tinling SP and Chole RA. Gerbilline Cholesteatoma Development I. Epithelial migration pattern and rate on the gerbil tympanic membrane: Comparisons with human and guinea pig, Oto-Head & Neck Surgery, 134: 788-793, 2006.
Wang EW, Jung JY, Pashia-Basse ME, Nason R, Scholnick SB, Chole RA. Otopathogenic Psudomonas aeruginosa as competent biofilm formers. Archives of Otolaryngology-Head & Neck Surgery, 131:983-989, November, 2005.
CONTACT INFORMATION
Richard A. Chole, M.D., Ph.D.
Department of Otolaryngology-Head and Neck Surgery
Washington University School of Medicine
Campus Box, 8115, 660 S. Euclid Ave.
St. Louis, MO 63110
http://oto.wustl.edu/chole/
Phone: (314) 362-7395
Fax: (314) 747-1004
Email address: rchole@wustl.edu