BIOGRAPHICAL SKETCH
Current Position:
Research Assistant Professor, Department of Otolaryngology
Research Assistant Professor (Joint), Program in Audiology and Communication Sciences
Education:
B.S., Psychology (Biology emphasis), University of California, 1982
M.S., Human Anatomy, University of California, 1989
Ph.D., Comparative Pathology, University of California. 1994
Links:
http://otocore.wustl.edu/
http://ent.wustl.edu/oto/otoweb.nsf/746682188a1bff2786256c5500627633/02e94f449b9a596f8625734c0068e0f7?OpenDocument
RESEARCH INTERESTS
Mechanisms of tissue destruction in the middle and inner ear (click for more information)

Click here for more information on Dr. Faddis's Lab.
PUBLICATIONS:
Faddis BT, Hasbani MJ and Goldberg MP (1997) Calpain activation contributes to dendritic remodeling after brief excitotoxic injury in vitro. J. Neurosci., 17(3):951-959.
Faddis BT and McGinn MD (1997) Spongiform degeneration of the gerbil cochlear nucleus: An ultrastructural and immunohistochemical evaluation. J. Neurocytol., 26 (9):625-635.
Chole, RA and Faddis BT (2002) Evidence for microbial biofilms in cholesteatomas. Arch. Otolaryngol. Head Neck Surg., 128:1129-1133.
Jung JY, Lin AC, Ramos LM, Faddis BT and Chole RA (2003) Nitric oxide synthase I mediates osteoclast activity in vitro and in vivo. J. Cell. Biochem., 89:613-621.
Tekkok, SB, Faddis BT and Goldberg MP (2005) AMPA/kainate receptors mediate axonal morphological disruption in hypoxic white matter. Neurosci. Lett., 382:275-9.
Dorsey DA, Masco D, Dikranian K, Hyrc K, Masciotra L, Faddis BT, Soriano M, Gru AA, Goldberg MP and de Erasquin GA. (2006) Ultrastructural characterization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-induced cell death in embryonic dopaminergic neurons. Apoptosis, 11:533-544.
Scholnick SB, Richter T, Houlihan PS and Faddis BT. Identification of a novel NOS1 promoter used during mouse osteoclastogenesis. Biochim. Biophys. Acta, Submitted-returned for revision.
Surgucheva I, Faddis BT and Surguchov A (2008) Synucleins in sensory tissues: localization and developmental changes. In preparation.
Faddis BT (2008) Essentials of cell structure and function: An introduction to cell biology. In: Anatomy and Physiology of Hearing for Audiologists. (William W. Clark and Kevin K. Ohlemiller, Eds.), Thomson Delmar Learning Publishers, Clifton Park, NY.
Faddis BT (2008) Structural and Functional Anatomy of the Outer Ear. In: Anatomy and Physiology of Hearing for Audiologists. (William W. Clark and Kevin K. Ohlemiller, Eds.), Thomson Delmar Learning Publishers, Clifton Park, NY.
Faddis BT (2008) Pathology of the Middle Ear. In: Anatomy and Physiology of Hearing for Audiologists. (William W. Clark and Kevin K. Ohlemiller, Eds.), Thomson Delmar Learning Publishers, Clifton Park, NY.
CONTACT INFORMATION
Brian Faddis, Ph.D.
Department of Otolaryngology
Washington University School of Medicine
Campus Box 8115, 660 S. Euclid Ave
St. Louis, MO 63110
Phone: (314) 747-3665
Fax: (314) 747-1004
Email address: faddisb@wustl.edu